Despite being a GH fragment, AOD9604 does not bind with high affinity to the HGH receptor and does not promote cell proliferation in HGH receptor-transfected cells
While its more common on the thighs and buttocks, many peopleespecially womenalso develop it on the stomach due to hormonal changes, weight fluctuations, ageing, or genetics
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They mimic natural peptides to regulate biological functions , making them useful for weight loss, muscle growth, skin rejuvenation, and overall health optimization
Difficulties arising from potential immunogenicity, large molecular weight, need for carriers for their delivery and instability in vivo are well recognized [188]
